Holly Yarbrough was born in Santa Monica, California. Her father, Glenn Yarbrough is a well-known recording artist with over seventy albums in his discography. Her Grandfather was a square dance caller in the Black Hills of South Dakota, and her Grandmother sang with the Paul Whiteman Orchestra.

Holly has studied at the Interlochen Arts Academy, Bard College and the Nashville Jazz Workshop. After attending at her Grandfather's bedside while he was in hospice care, she began volunteering for hospice through Compassion in Action.

Since 2006, she has worked for Alive Hospice in Nashville, Tennessee. She is currently pursuing certification as a therapeutic musician through the Music for Healing and Transition program.